This
inhibition may also be associated to the presence of aeudesmol,
naphthalene and d-cadinene for example previous
reports reveal that a-eudesmol was responsible for the
inhibition of neurogenic inflammation in models of the
electrical stimulation [27],while naphthalene derivatives are
currently used for the treatment of inflammatory disorders
[28]; Moreover, d-cadinene which was one of the main
components in the Teucrium essential oil exhibited antiinflammatory
activity [29]. Contents of essential oil from
C. validus may exert their effects by inhibiting the release of
mediators such as histamine and serotonin during the first
phase. Thus, both fresh and dry parts of the plant proved to
have significant anti-inflammatory properties.