As guided by the CHSCP theoretical framework, a number of factors were associated with the completion of the HAV/HBV vaccine series. Nursing strategies (NCMIT) were found to be critical in enhancing completion among these homeless and marginalized persons at risk of hepatitis. In addition, as presented among the findings, a number of sociodemographic (age, gender, recruitment site, and years homeless), psychosocial (being partnered), and behavior (same-sex behaviors and attending self-help programs for drugs or alcohol) factors also were associated with the completion of the vaccine series.