Calorie content
Since total calorie intake is what will impact body fat levels and weight gain, it’s the first factor to assess when comparing two foods. Both fructose and sugar are forms of carbohydrate, and contain four calories per gram consumed. Both also lack dietary fiber (which goes partially undigested through the body) and are generally lacking in nutritious value. There's not many health benefits of sugar or fructose here.
Sugar and high-fructose corn syrup are both composed of glucose and fructose; the only difference is that high-fructose corn syrup has a higher degree of fructose in it by about 5%