Flavonoids were known have biological activities such as antioxidant, anticancer and antimicrobial [33-36]. The kinds of flavonoid that have been isolated and have antioxidant activity were rutin and quercetin of mulberry leaves [37] and flavonol glycosides in the ethanol extract of Dendrophthoe pentandra (L.) Miq mistletoe [38]. Antioxidant activity of flavonoid shown by the basic structure in the form of flavan nucleus, which consists of 15 carbon atoms arranged in three rings (C6-C3-C8), labeled A, B and C (Fig. 1) [34]. In the basic structure of flavonoids, flavan nucleus, number, position and types of substititions effect in radical scavenging and chelating activity [39].