3.3. Effect of added water amount on MADG tablet disintegration time
The effect of the amount of added water on disintegration time was
investigated. Fig. 4 shows the disintegration time of MADG tablets as a
function of tensile strength. MADG tablets made with 0.0%, 1.0%, 2.0%,
and 3.0% added water were used for this evaluation.
Disintegration time of MADG tablets made with 0.0% water (80 s:
tensile strength 2.98 MPa) and 1.0% (75 s: tensile strength 3.24 MPa)
demonstrated fast disintegration compared to other tablets. Further increasing
the amount of added water increased the disintegration time
as shown in MADG tablets made with 2.0% water (105 s: tensile
strength 3.0 MPa) and 3.0% water (148 s: tensile strength 2.75 MPa).
These results suggested that the amount of added water may have a significant
impact on the disintegration time of MADG tablets.