Materials and methods: The antioxidant property was assayed by scavenging abilities using DPPH and
the anti-inflammatory activity was tested through the carrageenan-induced pleurisy model in mice. The
total phenolic compounds and flavonoid contents were determined spectrophotometrically.
Results: The ethanolic and butanol extracts (200 mg/kg, p.o.) presented a significant anti-inflammatory
activity toward carrageenan-induced pleurisy model in mice in comparison to dexamethasone
(0.5 mg/kg, s.c.). Among the parameters evaluated, the treatment with these samples inhibited leukocyte
migration and reduced the formation of exudate. The contents of flavonoids and total phenolic compounds
could be correlated with the antioxidant and anti-inflammatory activities observed for Capsicum
baccatum.