Introduction
Prolactin (PRL) is a polypeptide hormone primarily synthesized in the anterior pituitary that binds the prolactin receptor (PRLR), a member of the cytokine receptor superfamily. The long form of the PRLR possesses an intracellular domain that, upon PRL binding and dimerization, signals to the nucleus, activating genes involved in cellular processes such as proliferation, differentiation, and cell survival [1], [2], [3], [4] and [5].