Cysticercosis is generally viewed as a disease of developing countries or immigrants from areas where the disease is endemic. However, our review underscores that cysticercosis acquired in the United States can occur in many geographic regions of the country. Moreover, when looked for, a likely source of infection can frequently be found, principally among household members who are major sources of eggs and therefore infection. Like other fecal–oral-transmitted diseases, cysticercosis can be spread either directly or through contaminated food. Persons infected with the adult T. solium tapeworms are typically asymptomatic and may not be aware of their infection or of the potential risk to themselves and others. If hygiene is poor, transmission of eggs may occur, particularly within households where repeated opportunities for exposure exist. Even in areas where cysticercosis is endemic, the disease is recognized as a focal disease with clustering of cases identified around tapeworm carriers (27). This focal nature makes cysticercosis particularly amenable to public health follow-up and directed control efforts. The ability to find a probable source of infection among contacts to patients with cysticercosis shows that public health follow-up can be successfully conducted. Treatment of tapeworm carriers can eliminate them as possible sources of continuing infection. Such follow-up is routinely conducted by the Los Angeles County Department of Public Health.