Consumption of fruits and vegetables has been shown to be effective in the prevention of chronic
diseases. These benefits are often attributed to the high antioxidant content of some plant foods.
Apples are commonly eaten and are large contributors of phenolic compounds in European and
North American diets. The peels of apples, in particular, are high in phenolics. During applesauce
and canned apple manufacture, the antioxidant-rich peels of apples are discarded. To determine if
a useful source of antioxidants is being wasted, the phytochemical content, antioxidant activity, and
antiproliferative activity of the peels of four varieties of apples (Rome Beauty, Idared, Cortland, and
Golden Delicious) commonly used in applesauce production in New York state were investigated.
The values of the peels were compared to those of the flesh and flesh + peel components of the
apples. Within each variety, the total phenolic and flavonoid contents were highest in the peels, followed
by the flesh + peel and the flesh. Idared and Rome Beauty apple peels had the highest total phenolic
contents (588.9 ( 83.2 and 500.2 ( 13.7 mg of gallic acid equivalents/100 g of peels, respectively).
Rome Beauty and Idared peels were also highest in flavonoids (306.1 ( 6.7 and 303.2 ( 41.5 mg
of catechin equivalents/100 g of peels, respectively). Of the four varieties, Idared apple peels had
the most anthocyanins, with 26.8 ( 6.5 mg of cyanidin 3-glucoside equivalents/100 g of peels. The
peels all had significantly higher total antioxidant activities than the flesh + peel and flesh of the
apple varieties examined. Idared peels had the greatest antioxidant activity (312.2 ( 9.8 µmol of
vitamin C equivalents/g of peels). Apple peels were also shown to more effectively inhibit the growth
of HepG2 human liver cancer cells than the other apple components. Rome Beauty apple peels showed
the most bioactivity, inhibiting cell proliferation by 50% at the low concentration of 12.4 ( 0.4 mg of
peels/mL. The high content of phenolic compounds, antioxidant activity, and antiproliferative activity
of apple peels indicate that they may impart health benefits when consumed and should be regarded
as a valuable source of antioxidants.
Consumption of fruits and vegetables has been shown to be effective in the prevention of chronicdiseases. These benefits are often attributed to the high antioxidant content of some plant foods.Apples are commonly eaten and are large contributors of phenolic compounds in European andNorth American diets. The peels of apples, in particular, are high in phenolics. During applesauceand canned apple manufacture, the antioxidant-rich peels of apples are discarded. To determine ifa useful source of antioxidants is being wasted, the phytochemical content, antioxidant activity, andantiproliferative activity of the peels of four varieties of apples (Rome Beauty, Idared, Cortland, andGolden Delicious) commonly used in applesauce production in New York state were investigated.The values of the peels were compared to those of the flesh and flesh + peel components of theapples. Within each variety, the total phenolic and flavonoid contents were highest in the peels, followedby the flesh + peel and the flesh. Idared and Rome Beauty apple peels had the highest total phenoliccontents (588.9 ( 83.2 and 500.2 ( 13.7 mg of gallic acid equivalents/100 g of peels, respectively).Rome Beauty and Idared peels were also highest in flavonoids (306.1 ( 6.7 and 303.2 ( 41.5 mgof catechin equivalents/100 g of peels, respectively). Of the four varieties, Idared apple peels hadthe most anthocyanins, with 26.8 ( 6.5 mg of cyanidin 3-glucoside equivalents/100 g of peels. Theทั้งหมด peels มีกิจกรรมต้านอนุมูลอิสระรวมอย่างมีนัยสำคัญสูงกว่าเนื้อ + เปลือก และเนื้อของใบพันธุ์แอปเปิ้ลที่ตรวจสอบ Idared peels มีกิจกรรมต้านอนุมูลอิสระมากที่สุด (312.2 (9.8 µmol ของวิตามินซีเทียบเท่า/กรัมของ peels) Peels แอปเปิ้ลก็ยังแสดงได้อย่างมีประสิทธิภาพยับยั้งการเจริญเติบโตของเซลล์มนุษย์มะเร็งตับ HepG2 กว่าส่วนประกอบอื่น ๆ แอปเปิ้ล ความงามของโรมแอปเปิ้ล peels พบสุดทางชีวภาพ inhibiting การงอกเซลล์ 50% ที่ความเข้มข้นต่ำสุดของ 12.4 (0.4 มก.peels/mL เนื้อหาสูงของสารฟีนอ กิจกรรมการต้านอนุมูลอิสระ และกิจกรรม antiproliferativeของ peels แอปเปิ้ลระบุว่า พวกเขาอาจสอนสุขภาพเมื่อใช้ และควรถือเป็นแหล่งที่มีคุณค่าของสารต้านอนุมูลอิสระ
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