The new study, published today in the journal Nature Chemical Biology, represents a coup for scientists and drug companies that currently rely on extracting drugs like morphine and codeine directly from poppies and other plants, a process that’s expensive and can yield impurities that cause harmful side-effects. The discovery could mean cheaper medications — where biochemists brew large batches of pure opiates overnight rather than waiting months for poppy fields to grow. It could also have dangerous consequences if it falls into the wrong hands.
“This work is going to enable the production of novel [pain-relieving] analgesics that are safer and less addictive,” said MIT political scientist Kenneth Oye, who co-wrote an accompanying commentary for Nature Chemical Biology about possible regulations and was not involved with the research. “The other part of the equation is if those yeast strains work their way into broad circulation, then you’re talking about fundamental changes in illicit drug production and distribution.”