They leach into underground waters, moving along water pathways and eventually depositing in the
aquifer, or are washed away by run-off into surface waters thereby resulting in water and subsequently
soil pollution. Poisoning and toxicity in animals occur frequently through exchange and co-ordination
mechanisms. When ingested, they combine with the body’s biomolecules, like proteins and enzymes to
form stable biotoxic compounds, thereby mutilating their structures and hindering them from the
bioreactions of their functions. This paper reviews certain heavy metals and their biotoxic effects on
man and the mechanisms of their biochemical activities.