In the present study we have observed that UHPH-treatment of milk increased hydrolysis of as2-and b-cn and increased the levels of WSN and hydrophobic and hydrophilic peptides, possibly due to a more exposure of proteins to the proteolytic enzymes. However, not differences were found in the levels of TFFA with slightly dif- ferences in the FAA profile between UH- and PA-cheeses. According these results, the use of UHPH-treated milk does not adversely affect the development of cheese proteolysis, forming the basis of new knowledge that could lead UHPH a feasible treatment of goat milk for cheese production. Further investigations in sensorial characteristics of UH-cheeses are necessary to identify the effects of this treatment in cheese characteristics.