In this paper, we report a novel and facile approach for the
fabrication of μPADs via the hydrophobization of the filter
paper by coupling octadecyltrichlorosilane (OTS) to paper
fibers, followed by UV-lithography of the OTS coating. The
silanization reaction between the OTS and filter paper and the
feasibility of wettability-patterning of the OTS-coated paper
(abbreviated as OTS-paper) via region-selective UV degrading
of the coated OTS were investigated. The μPADs prepared
with the developed approach were demonstrated for colorimetric
assays of nitrite ions in food samples