L-thyroxine replacement therapy may be required in those with transient or prolonged hypothyroidism
that can occur in individuals with severe, diffuse inflammation and necrosis of the gland. Local complications also include: vocal cord paralysis, abscess rupture or extension into adjacent sites and organs (anterior mediastinum, trachea, esophagus), thrombosis of the internal jugular vein (Lemiere’s syndrome), and extrinsic compression of the trachea [24].