Results were generalized into three themes that addressed the interaction-in-transition between patients and their families. These themes were: "All of the blame comes from the disease", "There is love in the family", and "Agreement to start over". Nurses increased their positive interaction with the family by facilitating cognitive, emotional, and behavioral change in the family. The 3 nursing strategy interventions used in this study to promote family adaptation in this study were: (1) guiding family experiences of the disease situation; (2) inspiring the potential strength in the families; (3) mobilizing the internal and external resources of families.