Most visitors come to Amphawa on a day-trip from Bangkok. You can take the fast mini van from Victory Monument to Damnoen Saduak and get off at Amphawa. A bus from the Southern Bus Terminal might be a safer option but you have to take the bus to Samut Songkhram first and switch onto a songthaew or bus heading for Amphawa. Ask the locals, as buses are only signed in Thai and songthaews don't have any signs at all. The ride will take about 15 minutes and it is obvious where to get off.