In an analysis of fluoride release from fissure sealants,
Garcia-Godoy, Summitt and Donly found that all the fluoridated
sealants tested released measurable fluoride
throughout the test period in a similar pattern. However,
the greatest amount of fluoride was released in the first 24
hours after mixing, and the fluoride release fell sharply on
the second day and decreased slowly for the last days.9