Generally , enzyme in solution or in food systems are stable to dehydration, provided the temperature is controlled to prevent thermal inactivation. Indeed , lyophilization is used routinely to prepare active enzyme powders from solutions. During the controlled drying of grains , many endogenous enzyme remain active. Removal of water from biomaterials with organic solvents also can lead to retention of enzyme activity , provided the temperature is maintained at 0 or less. The composition of the medium in which the enzyme is suspended can influence retention of enzyme activity ; methylamines , carbohydrates , and amino acids can stabilize proteins in dry or high osmotic environments