ABSTRACT: This study aimed to determine the association between indoor air quality and
the prevalence of sick building syndrome (SBS) among office workers in new and old
buildings in Universiti Putra Malaysia, Serdang. A cross-sectional comparative study was
conducted among 139 office workers from new buildings (The Faculty of Medicine and
Health Sciences and Faculty of Engineering) and old building (administrative building of
UPM). The SBS symptoms were assessed by using the questionnaires of Indoor Air Quality
and Work Environment Symptoms Survey, NIOSH Indoor Environment Quality Survey
(1991) while for the IAQ and IAP they were monitored by using the instruments. The results
showed that ventilation rate was significantly higher in new buildings compared to old
building with median 21.28 cfm/person and 15.16 cfm/person, respectively (z= -2.722,
p