Inhaled zanamivir (two puffs, 10 mg, twice daily) does not
require dose adjustment either for hepatic or renal failure.
Oral oseltamivir (75 mg twice daily) dose adjustment is not
needed in hepatic impairment but doses should be modified in
renal insufficiency according to the recommendations included
in Table 3. Proven benefits of higher doses of oseltamivir in
SOT recipients with severe influenza infection are lacking