The dual expression of O4 epitope and neuronally associated
-tubulin III in response to in vitro neurogenic culture
further supports the neurogenic potential of the nasally derived
cells. Under neurogenic conditions used in this study, however,
central depot cells seemed to express more neuronal and glial
associated antigens than the nasal depot-derived cell lines. The
reason for the disparity between the CD marker expression and
neurodifferentiation data is not known. However, the results
may simply reflect differences in differentiation signaling capacity
inherent to the different developmental origins of the depots or
may be due to differences in differentiation capacity acquired
during in vitro cell culture.