HIV Protease Inhibitors Saquinavir and other HIV protease inhibitors Upon co-administration with with a similar associated the plasma concentrations of intravenous midazolam increased by 5 with HIV protease inhibitors, increase in terminal half-life. If parenteral lam is co-administered ketoconazole within azole treatment setting shoul follow the description in the section above for antifungals (see Precautions)