whereas its chronic administration could lead to irreversible renal failure with hypocellular interstitial fibrosis by inducing cellular apoptosis and transdifferentiation or by directly activating interstitial myofibrotic cells.
whereas its chronic administration could lead toirreversible renal failure with hypocellular interstitialfibrosis by inducing cellular apoptosis and transdifferentiationor by directly activating interstitial myofibroticcells.