Although providing nutritional support to critically ill patients can alter nutritional outcomes, there are few RCTs
conclusively demonstrating that any form of nutritional support improves the morbidity and mortality of critically ill
patients. The absence of data does not mean that nutritional support is ineffective. In many cases, it means that these
studies have not been done, and we cannot make strong clinical recommendations. The possibility exists that
nutritional support may do more harm than good.