USA) was added to the glass tubes. A violet color indicated bacterial growth. The tubes were evaluated for color change on day 8. For standard tests, the MIC values of rifampin and isoniazid (Sigma, New Jersey, USA) were determined each time. The acceptable minimum inhibitory concentration (MIC) ranges of these drugs were 0.50-0.03 μg ml-1, respectively. The MIC of each oil corresponded to the lowest concentration at which the bacteria tested did not show growth. Susceptibility testing was performed 3 times. The results were expressed as the mean of the three tests. Results were expressed as geometric mean (GM) ± standard error of the mean (s) of the MICs.
Antimycobacterial time kill curves