Follow-up and HIV-1 incidence
Median follow-up for HIV-1 seropositive and HIV-1
seronegative partners was 20.9 [interquartile range (IQR)
15.6–24.1] and 19.9 months (IQR 14.3–23.9), respectively.
For HIV-1 seronegative partners, 5141 person-years
of follow-up (1695 among HIV-1 seronegative women
and 3446 among HIV-1 seronegative men) were accrued
for assessment of HIV-1 seroincidence, during which 151
HIV-1 seroconversions occurred (61 in women and 90
in men).
Among women, overall HIV-1 incidence was
3.60 cases per 100 person-years. Of the 90 incident HIV-1
infections in men, 58 (64.4%) were determined by viral
sequencing to be genetically linked within the partnership for an incidence of linked transmission of 1.68 cases
per 100 person-years.