Oxyresveratrol (1, 10mM) also inhibited glutamate release into medium and reactive oxygen species (ROS) generation
induced by 10mM Ab (25—35). These results suggest that oxyresveratrol prevents Ab (25—35)-induced
neuronal cell damage by interfering with the increase of [Ca2]c, and then by inhibiting glutamate release and
ROS generation. Furthermore, these effects of oxyresveratrol may be associated with the neuroprotective effect
of Smilacis chinae rhizome.