Risk Factors
• The etiology of ovarian cancer is not well understood but is believed to be a combination of hormonal, environmental, and genetic factors.1,2
• Age: Most ovarian cancers occur after menopause.1,2
• Family history of ovarian, breast, or colorectal cancer. The more relatives who have ovarian cancer, both on the maternal and paternal side, the higher the risk.1,2
o About 5% to 10% of ovarian cancers are inherited.
o The risk is higher if the patient has a history of breast or colon cancer or the presence of the breast cancer gene 1 (BRCA1) or BRCA2 gene mutation.
o Women of Jewish descent have a higher risk.
• Nulliparous women have an increased risk of ovarian cancer, as do those who have used infertility drugs.1,2
• Postmenopausal women who took hormone replacement therapy (HRT), especially estrogen therapy alone, for 5 to 10 years have an increased risk of ovarian cancer.1,2
• Obesity increases the risk of ovarian cancer; compared with women of normal weight, those who are overweight have a higher rate of death.1,2
• Oral contraceptives reduce risk of ovarian cancer by 30% to 60% after as little as 3 to 6 months. There is further evidence that oral contraceptives continue to confer protection for years and even decades after women stop using them.1,2
Risk Factors
• The etiology of ovarian cancer is not well understood but is believed to be a combination of hormonal, environmental, and genetic factors.1,2
• Age: Most ovarian cancers occur after menopause.1,2
• Family history of ovarian, breast, or colorectal cancer. The more relatives who have ovarian cancer, both on the maternal and paternal side, the higher the risk.1,2
o About 5% to 10% of ovarian cancers are inherited.
o The risk is higher if the patient has a history of breast or colon cancer or the presence of the breast cancer gene 1 (BRCA1) or BRCA2 gene mutation.
o Women of Jewish descent have a higher risk.
• Nulliparous women have an increased risk of ovarian cancer, as do those who have used infertility drugs.1,2
• Postmenopausal women who took hormone replacement therapy (HRT), especially estrogen therapy alone, for 5 to 10 years have an increased risk of ovarian cancer.1,2
• Obesity increases the risk of ovarian cancer; compared with women of normal weight, those who are overweight have a higher rate of death.1,2
• Oral contraceptives reduce risk of ovarian cancer by 30% to 60% after as little as 3 to 6 months. There is further evidence that oral contraceptives continue to confer protection for years and even decades after women stop using them.1,2
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Risk Factors
• The etiology of ovarian cancer is not well understood but is believed to be a combination of hormonal, environmental, and genetic factors.1,2
• Age: Most ovarian cancers occur after menopause.1,2
• Family history of ovarian, breast, or colorectal cancer. The more relatives who have ovarian cancer, both on the maternal and paternal side, the higher the risk.1,2
o About 5% to 10% of ovarian cancers are inherited.
o The risk is higher if the patient has a history of breast or colon cancer or the presence of the breast cancer gene 1 (BRCA1) or BRCA2 gene mutation.
o Women of Jewish descent have a higher risk.
• Nulliparous women have an increased risk of ovarian cancer, as do those who have used infertility drugs.1,2
• Postmenopausal women who took hormone replacement therapy (HRT), especially estrogen therapy alone, for 5 to 10 years have an increased risk of ovarian cancer.1,2
• Obesity increases the risk of ovarian cancer; compared with women of normal weight, those who are overweight have a higher rate of death.1,2
• Oral contraceptives reduce risk of ovarian cancer by 30% to 60% after as little as 3 to 6 months. There is further evidence that oral contraceptives continue to confer protection for years and even decades after women stop using them.1,2
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