Glucuronic acid-a human detoxifying drug can be found in traditional kombucha which is a sweetenedblack tea fermented by symbiotic microflora between yeast and acetic acid bacteria embedded within a microbial cellulose membrane. The main purpose of the study is to obtain the new designed symbiosis from the isolated yeasts and bacterial strains which can produce the high-level glucuronic acid kombucha and avoid unexpected microbial contaminants.