Microsimulation models allow for variability between patients [25] as patients are considered
individually in the model. Each patient travels through the model one at the time, with the model being
able to accommodate patients’ individual characteristics and their disease history/progression. An
example of a microsimulation model is the United Kingdom Prospective Diabetes (UKPDS) model. It
was developed by Clarke et al [29] and further adapted and used to model other conditions. The model
consists of an integrated system of parametric risk equations allowing for estimation of seven diabetes
complications and their associated costs and outcomes.