This study demonstrated that fresh consumption of pomegranate is the most preferred, followed by juice without peel and wine with peel. Considering the seasonality and territoriality, the pomegranate juice processing will be indispensable. Juicing with peel made the juice taste bitter and astringent, and looks dark and unpleasant, but contributed better sensory quality to the wine than juicing without peel, and pomegranate wine with peel will be the most welcome product. When juicing with peel, total polyphenol and flavonoid contents of fresh juice and its processing products increased, and total polyphenol, flavonoid and anthocyanin content fluctuated more dramatically during wine making than storable juice processing. When juicing with peel, total polyphenol content of the fermentation liquids fluctuated very much, and flavonoid and anthocyanins were obviously lost after fermentation. Total polyphenol and anthocyanin content of the fresh juicing decreased much and flavonoids changed less after storable juice processing. Therefore, juicing with peel will result in some difficulties to control physicochemical characteristics and juice without peel is the most cost-effective product in industrial procrssing. Additionally, as compared to storable juice processing, fermentation will take long a time and lead to phenolics composition changs. It seems that pomegranate wine with peel is a better choice considering the flavor, phenolics content amd antioxidant potential. Purified polyphenols from wine and juice had different performance on the 6 antioxidant activities assays. Polyphenols of the pomegranate juice products containing peel substances showed higher total reducing ability, DPPH+ and ABTS+ radical elimination ability in vitro, but their hydroxyl radicals clearance activity was not so good, and their superoxide anion radical elimination ability had no significant difference when compared to that of juice products without peel substances. Comprehensively considering customer preference, production techniques and antioxidant activities, juice without peel and wine with peel are worthy of recommending on for production and consumption