It is well documented that in diabetes melli-tus immune cells, such as macrophages and neutro-phils are impaired, possibly leading to an increased susceptibility to infections including those caused by Gram-negative bacteria.4 It has been shown that in-sulin levels are associated with bacteremic melioido-sis.5 To date, the status of IL-17 expression associ-ated with B. pseudomallei infection and diabetes mellitus has not been established. Thus the present study was conceived to investigate the possible in-volvement of IL-17 expression in the pathogenesis of