Riceberry, a black purple rice variety (Oryza Sativa L.), is a new breeding line developed by the Rice Research Center,
Kasetsart University, Kamphaeng Saen, Nakhon Pathom, Thailand. Recently, Leardkamolkarn et al. (2011) reported that
a crude extract of riceberry bran contains two major bioactive compounds (trimethylapigenin and triterpenes) and two
major anthocyanins (cyanidin-3-glucoside, and peonidin-3-glucoside) that are able to reduce inflammation (Adriano
et al., 2006). Therefore, riceberry bran was used in this study as a major ingredient to formulate into dietary riceberry supplement (RB). High fat (HF)-fed rat treated with steptozotocin (STZ) is a widely used animal model of T2DM as it produces many of the characteristics of T2DM, such as insulin resistance or reduced insulin secretion, abnormal lipid profiles as well as b-cell dysfunction (Srinivasan & Ramarao, 2007).