Bromelain is an extract derived from the stems of pineapples, although it exists in all parts of the fresh plant and fruit, which has many uses. The extract has a history of folk and modern medicinal use. As a supplement, it is thought to have anti-inflammatory effects. Bromelain also contains chemicals that might interfere with the growth of tumor cells and slow blood clotting, but no peer-reviewed research shows any efficacy against tumors. As a culinary ingredient, it is used primarily as a tenderizer.
The term "bromelain" may refer to either of two protease enzymes extracted from the plants of the family Bromeliaceae, or it may refer to a combination of those enzymes along with other compounds produced in an extract.
The US National Institute of Health rates bromelain as only possibly effective against osteoarthritis, but only when taken in combination with trypsin and rutin (Phlogenzym).[1] The same institute has stated it is possibly ineffective for preventing postexercise muscle tiredness. In addition, no evidence indicates efficacy of the product for any other disorder.[1]