L-DOPA content of ethanolic extract of Mucuna pruriens seed has
been reported to be responsible for aphrodisiac activity (Suresh
et al., 2009. In our in vitro study, methanolic extract of Mucuna
pruriens failed to inhibit ROCK-II. However, successive aqueous
extract of Mucuna pruriens showed reasonably good ROCK-II inhibition
indicating that this extract probably contains other active constituents. Hence, Butea frondosa, Syzygium aromaticum, Butea
superba, Chlorophytum borivilianum and Mucuna pruriens seem to be
acting through at least two different mechanisms including ROCK-II
inhibition.
L-DOPA content of ethanolic extract of Mucuna pruriens seed hasbeen reported to be responsible for aphrodisiac activity (Sureshet al., 2009. In our in vitro study, methanolic extract of Mucunapruriens failed to inhibit ROCK-II. However, successive aqueousextract of Mucuna pruriens showed reasonably good ROCK-II inhibitionindicating that this extract probably contains other active constituents. Hence, Butea frondosa, Syzygium aromaticum, Buteasuperba, Chlorophytum borivilianum and Mucuna pruriens seem to beacting through at least two different mechanisms including ROCK-IIinhibition.
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