In the present work, the mechanical, thermal, and morphological properties of PLA/EPO blends at different EPO loadings have been investigated. The optimum EPO loading for enhanced mechanical and thermal properties of PLA/EPO is 1 wt%. SEM results evidence good interfacial adhesion between the two phases of the PLA matrix and EPO. This is indirectly reflected in improved tensile, flexural and impact properties of the blend by 5%, 6% and 10%, respectively. Moreover, DMA measurements indicate that the plasticization with 1 wt% EPO leads to a decrease in storage modulus, due to an improved flexibility of the PLA. From the DSC results, a shift to lower glass transition temperature was observed due to an increase in the mobility of polymer chains by the addition of EPO. This composition also displayed lower crystallinity, indicating it is amorphous. In addition, TGA thermograms revealed a substantial increase in the matrix degradation temperatures and thermal stability by 28.5%. Considering all the analyses performed, it can be concluded that these blends enhanced the overall properties of neat PLA. This makes PLA/1 wt% EPO blend an interesting multifunctional material for possible industrial applications.