The crude methanol extract of the stem bark of
Limonia acidissima L. and its different organic
soluble partitionates were screened for cytotoxic and
antioxidant activities. The brine shrimp lethality
bioassay was used to evaluate the cytotoxicity. The
petroleum ether soluble fraction (PESF) of the
methanolic extract exhibited strong cytotoxic activity
(LC50 = 2.0779 μg/ml). On the other hands
chloroform soluble fraction of the methanolic extract
showed the highest free radical scavenging activity
with IC50 value 18.80 μg/ml.
The plant L. acidissima (Family- Rutaceae) is
known as Kath bael in Bangla and is a common plant
of Bangladesh. Its leaves, bark and then fruits have
medicinal values and used as traditional medicines
for centuries due to their antimicrobial,1 antifungal,2,3
astringent, anti-inflammatory4 and insulin
secretogouge5 activities. In the south Asian countries
like Mayanmar, Thailand etc., the bark of the tree is
used as a popular natural cosmetic.6 Different parts
of the plant are also used