The U.S. Surgeon General’s report (12) recommended that most people accumulate ≥30 min of moderate-intensity activity on most, ideally all, days of the week. However, most clinical trials evaluating exercise interventions in people with type 2 diabetes have used a three-times-per-week frequency (6), and many people find it easier to schedule fewer longer sessions rather than five or more weekly shorter sessions. The effect of a single bout of aerobic exercise on insulin sensitivity lasts 24–72 h depending on the duration and intensity of the activity (20). Because the duration of increased insulin sensitivity is generally not >72 h, we recommend that there should not be more than 2 consecutive days without aerobic physical activity. The effect of resistance exercise training on insulin sensitivity may last somewhat longer (21), perhaps because some of its effects are mediated by increases in muscle mass.