Finally, patients can easily be treated with both RF and HA filler simultaneously. Most previous combination regimens included serial treatment that are not performed on the same day because of concerns about adverse effect,although Goldman et al. Reported that combined therapies of laser or RF treatment immediately after filler injection are also safe. Nonetheless, no significant differences have ever been identified between combined therapies and treatment with filler alone. Additionally, previous combination treatment regimens required more time and effort for coordination and treatment delivery than the new needle RF device described in the present study