SCD causes harmful pathophysical effects, including sickling,
vaso-occlusion, and ischemia-reperfusion injury. These
complications have a cyclic nature which involve the generation
and impairment of oxidative stress. Studies have shown relationships
between markers of oxidative stress and common secondary
diseases in SCD, such as ACS and PHT (7, 8). Although
there is elevated oxidative stress in SCD, these markers can
also be mediated by other outside factors such as diet, physical
activity, environment, and other comorbid diseases associated