The amount of
rutin deposited in the epidermal and the dermal layers (excluding
the stratum corneum) increased in the following order: ethosome
(9.30%; 8.68±0.03 µg/cm2
)>liposome (6.78%; 6.33±1.34 µg/cm2
)>
ethanolic solution (6.57%; 6.13±0.14µg/cm2
)>DW solution (4.05%;
3.78±0.13 µg/cm2
).