Sea lettuce (Ulva spp.) is useful for both nutrition and waste water treatment. With some characteristics of algae that can tolerate and growth well. The factors affecting growth include light, temperature, salinity, nutrients. The data indicated that lettuce seaweed can growth at light intensity of 3.7 kilolux. The optimum water salinity and temperature are ranging from, 15-25 psu and 17-22 degrees Celsius, respectively water-soluble nitrogen in the form of nitrates. Is the most efficiency on growth enhancement.