This review included 26 studies involving 8021 participants. Overall the studies were of reasonable quality, but one study was consideredat high risk of bias. Fiftee n studies evaluated predominantly organisational interventions and 11 studies evaluated educational andbehavioural interventions for patients. Results were pooled where appropriate, although some clinical and methodological he terogeneitywas present. The estimated effects of organisational interventions were compatible with improvements and no differences in themodifiable r isk factors mean systolic blood pressure (mean difference (MD) -2.57 mmHg; 95% confidence interval (CI) -5.46 to0.31), mean diastolic blood pressure (MD -0.90 mmHg; 95% CI -2.49 to 0.68), blood pressure target achievement (OR 1.24;95% CI 0.94 to 1.64) and me an body mass index (MD -0.68 kg/m2; 95% CI -1.46 to 0.11). There were no significant effectsof organisational interventions on lipid profile, HbA1c, medication adherence or recurrent cardiovascular events. Educational andbehavioural interventions were not generally associated with clear differences in any of the review outcomes, with only two exceptions.