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possibility of large-scale production using natural ingre- dients and entrapment and release of water-soluble, lipid- soluble, and amphiphilic materials as well as targetability [3,4], liposomes have been widely used in the food sector both in research and in industry. Liposome manufacture requires input of energy for dispersion of lipid/phospho- lipid molecules in an aqueous medium. The main objec- tive of such process is to obtain vesicles with the right size, acceptable polydispersity, elasticity, structure and encapsulation efficiency [4,5]. Different methodologies are described in the literature to produce multi-lamellar vesicles (MLVs), large unilamellar vesicles (LUVs) and