Dementia
Hypertension is also a recognized risk factor for later cognitive
decline and dementia, both vascular and Alzheimer’s dementia.
Several hypertension trials have included dementia as a secondary
outcome allowing some insight into the benefit or not of BP lowering
on incident dementia.
Various longitudinal open-label or active comparator trials have
reported cognitive function results and shorter trials have looked
at neuropsychological outcomes and antihypertensive use over
periods of several weeks. Four double-blind placebo-controlled