Hyperinsulinemia and hyperglycemia in the intrauterine environment is common in pregnancies complicated
by diabetes, what cause bigger fetal organs development than they should be and therefore favors the emergence
of macrosomia. Moreover, the excessive and continuous supply of glucose, amino acids and lipids from the
mother to the fetus stimulates the increase of newborn weight. Other determinant factors of fetal growth and additional
elements such as the presence of some hormones triglycerides, of free fatty acids, ketones, leptin, amino
acids and growth factors insulin-like (IGF) and insulin, are recognized as causative agents of exacerbated fetal
development