Our study aimed at targeting ceramide metabolic pathway to
induce apoptosis in human breast cancer cell lines. Numerous acid
ceramidase inhibitors are available in market and N-Oleoyl ethanolamine,
B13, D-MAPP, D-NMAPPD and DM102 have been reported
to induce apoptosis in colon, prostate, glioma, melanoma
and breast cancer cell lines