Porous materials of bombyx mori silk sericin were prepared freeze-drying. The effects of concentration of the sericin solution and that of freezing temperature on the structure and properties of material were investigated the results indicated thatbporous sericin materials with aver-age pore radius between 60 and 90 and porosity between 75 and 85% could be prepared by freeze-drying. Thicker solution and lower freezing temperature resulted in smaller pore radius and porosity and moreover bigger pore density the condensed structure of interior sericin was mainly amorphous and contrained some crystal structure compared to the non-crosslinked porous sericin materials the content of the sheet structure of the sericin materials cross-linked by poly diglycidyl ether in creased to some extent.