The PS fraction reduced the lesions by 50% at 50 and 100 mg/kg (no dose response was observed) with similar effect than the PI fraction at 450 mg/kg. In the aspirin-induced gastric ulcer, the best gastroprotective effect was found in the PS fraction, which inhibited lesions by nearly 100% at 12.5 mg/kg. In our experimental conditions, the PS extract at doses ≥12.5 mg/kg proved to be more active than ranitidine at 50 mg/kg.