Establish vascular access. For products containing cellular components (RBCs, WBCs), use an 18- to 20-G catheter for optimal patient comfort and flow rate. If necessary, needles and IV catheters used for infusion of cellular components may be as small as 24 or 25 G. If using the smaller gauges, dilution with normal saline or Plasma-Lyte 148 and the use of an IV pump may be helpful in maintaining the infusion. Larger gauges allow more rapid rates of infusion.